Gotkowski^Karol  ·  DKFZ Heidelberg Div. Medical Image Computing  ·  Series 001
Portrait of Karol Gotkowski
Karol Gotkowski
Heidelberg, Germany

Karol
Gotkowski

Machine Learning Engineer and Researcher at the German Cancer Research Center (DKFZ), working on 3D radiological image analysis and foundation models.

fig. 0 — a field of isocontoursmove to probe
01About

Teaching models to see in three dimensions, from millions of CT and MRI volumes.

I’m a Machine Learning Engineer and Researcher at the Medical Image Computing group of the Deutsches Krebsforschungszentrum (DKFZ) in Heidelberg, Germany, specializing in 3D radiological image analysis. Over the last two years, my work has strongly focused on large-scale self-supervised representation learning for medical imaging, alongside interactive and applied segmentation research.

Co-lead of the Human Radiome Project, which aims to develop a radiological 3D vision foundation model trained on 4.8 million 3D images to improve diagnostics and support treatment decisions across diverse populations.

Frequent maintainer, contributor and daily user of nnU-Net, and many of my projects build upon its philosophy of strong, generalizable baselines extended toward interactive and foundation-model–based systems.

2.5M+
3D volumes in DINOv2 pretraining
4.8M
3D images targeted by the Human Radiome Project
9.0k★
nnU-Net, which I help maintain
02Research
  1. Large-scale self-supervised representation learning DINOv2 / DINOv3

    My main research focus over the past two years has been DINO-based foundation models for medical imaging. Within the Human Radiome Project I worked extensively with DINOv2, contributing to large-scale pretraining on more than 2.5 million 3D CT and MRI volumes. I currently work with DINOv3, focusing on parameter-efficient fine-tuning (PEFT) strategies across medical and non-medical image domains.

  2. Methodological & interactive deep learning

    3D medical image segmentation methods with an emphasis on weak supervision, interactive and prompt-based segmentation, and usability-driven model design, including large-scale benchmarking, Napari-based interactive systems, and scalable training and inference pipelines.

  3. Applied & clinical projects

    Collaboration with clinical partners on applied radiological segmentation tasks, translating methodological advances into clinically meaningful and validated systems.

  4. Tooling & infrastructure

    Design and maintenance of open-source tools for patch-based processing, large-volume data handling, compressed storage, experiment configuration, and reproducible research workflows.

03Open source
04Selected
publications